Hazard search
Methylene diphenyl diisocyanate
- CAS number
- 101-68-8
- Also known as
- 4,4-methylene bisphenyl isocyanate · 4,4-Methylene bisphenyl isocyanate (MDI) (isocyanates) · 4,4-Methylene diphenyl isocyanate (MDI) · 4,4-Methylenebisphenyl isocyanate (MDI) (isocyanates, total) · Diphenylmethane-4,4'-diisocyanate (4,4-methylene bisphenyl isocyanate) (isocyanates) · Diphenylmethane-4.4'-diisocyanate · MDI · MDI (4,4'-methylenebisphenyl isocyanate) (isocyanates) · MDI (4,4-methylenebis[phenyl isocyanate]) (isocyanates, total) · Methylene bisphenyl isocyanate (MDI) · p,p'-Diphenylmethane diisocyanate
UK workplace exposure limits
| Limit | Value | Applies to |
|---|---|---|
| 8-hour TWA | 0.02 mg/m³ | |
| 15-minute STEL | 0.07 mg/m³ |
Notations
- Sen: can cause sensitisation
Sampling methods
| Method | Sampling | Medium | Analysis | Part numbers |
|---|---|---|---|---|
| MDHS 25/4 Organic Isocyanates in air (aerosols) by HPLC -EC Method document (opens in a new tab) | Active (pump) | Midget impinger & coated glass fibre filter | 225-36-4 225-22 | |
| MDHS 25/4 Organic Isocyanates in air (vapours only) by HPLC -EC Method document (opens in a new tab) | Active (pump) | Stainless Steel IOM with coated glass fibre filter | 225-79A | |
| MDHS 25/4 Organic Isocyanates in air (aerosols per Appendix 2) by HPLC -EC Method document (opens in a new tab) | Active (pump) | Stainless Steel IOM with coated glass fibre filter(s) | 225-79A | |
| NIOSH 5521 Isocyanates (monomeric) by HPLC -ECD/UV Method document (opens in a new tab) | Active (pump) | Midget impinger | HPLC-ELCHM & HPLC-UV | 225-36-1 225-22 |
| NIOSH 5522 Isocyanates by HPLC -FD/ECD Method document (opens in a new tab) | Active (pump) | Midget impinger | HPLC-FD | 225-36-1 225-22 |
| NIOSH 5525 Isocyanates (total) by HPLC/UV Method document (opens in a new tab) | Active (pump) | Stainless steel IOM + GF filter | HPLC-UV | 225-76A 225-702 225-7 225-4 225-27 |
| OSHA 5002 Organic Vapour Samplin gGroup 3-diisocyanates- by UHPLC-FD Method document (opens in a new tab) | Active (pump) | Glass fibre filter & support pad in open face cassette | HPLC-UV or HPLC-FD | 225-9002 225-9013 225-4 |
| OSHA 5002 Organic Vapour Sampling Group 3 by UHPLC-FLR Method document (opens in a new tab) | Active (pump) | Open-face cassette with Glass Fibre Filter & support pad (page 2 of method) | 225-3250 225-7 225-27 |
Methods and limits as published by their agencies and summarised by SKC; check the current method and the limit that applies to you before sampling.
Source: SKC Ltd (UK), Hazard Search, used with SKC's permission (opens in a new tab); SKC Inc. (USA), Sampling Guides, used with SKC's permission (opens in a new tab)