--- title: "Methyl isobutyl ketone (108-10-1): sampling methods" url: https://analyt-mtc.com/tools/hazard-search/methyl-isobutyl-ketone-108-10-1/ lang: en alternates: en: https://analyt-mtc.com/tools/hazard-search/methyl-isobutyl-ketone-108-10-1/ de: https://analyt-mtc.com/de/tools/gefahrstoffsuche/methyl-isobutyl-ketone-108-10-1/ --- Hazard search # Methyl isobutyl ketone CAS number 108-10-1 Also known as 4-Methyl-2-pentanone · 4-Methylpentan-2-one · Hexone · Hexone (Ketones I) · Hexone (methyl isobutyl ketone \[MIBK\]) · Hexone (methyl isobutyl ketone) (Ketones I) · Isopropylacetone · Methyl isobutyl ketone (hexone) · Methyl isobutyl ketone (hexone) (MIBK) · Methyl isobutyl ketone (hexone) (see online Passive Sampling Guide) · Methyl isobutyl ketone (Ketones I) · Methyl isobutyl ketone (MIBK) · Methyl isobutyl ketone (MIBK), (hexone) · MIBK · MIBK (see methyl isobutyl ketone) ## UK workplace exposure limits | Limit | Value | Applies to | | --- | --- | --- | | 8-hour TWA | 50 ppm | | | 8-hour TWA | 208 mg/m³ | | | 15-minute STEL | 100 ppm | | | 15-minute STEL | 416 mg/m³ | | ### Notations - BMGV: a biological monitoring guidance value exists - Sk: can be absorbed through the skin ## Sampling methods | Method | Sampling | Medium | Analysis | Part numbers | | --- | --- | --- | --- | --- | | **MDHS 72** / VOCs by thermal desorption and GC / [Method document (opens in a new tab)](https://www.hse.gov.uk/pubns/mdhs/pdfs/mdhs72.pdf) | Active (pump) | Tenax (250mg) or Chromosorb 106 (300mg) thermal desorption tube | TD, GC | [226-357](https://analyt-mtc.com/catalog/product/skc-tenax-sorbent-tubes/#part-226-357) / [226-358](https://analyt-mtc.com/catalog/product/skc-chromosorb-sorbent-tubes/#part-226-358) | | **MDHS 80** | Active (pump) | | TD, GC | [226-357](https://analyt-mtc.com/catalog/product/skc-tenax-sorbent-tubes/#part-226-357) | | **MDHS 88** / VOCs by solvent desorption and GC / [Method document (opens in a new tab)](https://www.hse.gov.uk/pubns/mdhs/pdfs/mdhs88.pdf) | Passive | Passive sampler | GC-FID | [575-001](https://analyt-mtc.com/catalog/product/skc-organic-vapour-passive-samplers/#part-575-001) / [575-002](https://analyt-mtc.com/catalog/product/skc-organic-vapour-passive-samplers/#part-575-002) | | **MDHS 96** / VOCs by solvent desorption and GC / [Method document (opens in a new tab)](https://www.hse.gov.uk/pubns/mdhs/pdfs/mdhs96.pdf) | Active (pump) | Charcoal tube (100/50mg) | GC-FID | [226-01](https://analyt-mtc.com/catalog/product/skc-anasorb-sorbent-tubes/) | | **MDHS 104** / VOCs by solvent desorption and GC / [Method document (opens in a new tab)](https://www.hse.gov.uk/pubns/mdhs/pdfs/mdhs104.pdf) | Active (pump) | Charcoal tube (100/50mg) | | [226-01](https://analyt-mtc.com/catalog/product/skc-anasorb-sorbent-tubes/) | | **MDHS 104** / VOCs by thermal desorption and GC / [Method document (opens in a new tab)](https://www.hse.gov.uk/pubns/mdhs/pdfs/mdhs104.pdf) | Active (pump) | Tenax TA Tube (250 mg) or Chromosorb 106 Tube (300 mg) | | [226-357](https://analyt-mtc.com/catalog/product/skc-tenax-sorbent-tubes/#part-226-357) / [226-358](https://analyt-mtc.com/catalog/product/skc-chromosorb-sorbent-tubes/#part-226-358) | | **NIOSH 1300** / Ketones by GC-FID / [Method document (opens in a new tab)](http://www.cdc.gov/niosh/docs/2003-154/pdfs/1300.pdf) | Active (pump) | Charcoal tube (100/50mg) | GC-FID | [226-01](https://analyt-mtc.com/catalog/product/skc-anasorb-sorbent-tubes/) | | **NIOSH 2500** | Active (pump) | | GC-FID | [226-81A](https://analyt-mtc.com/catalog/product/skc-anasorb-sorbent-tubes/#part-226-81a) | | **NIOSH 2549** / VOCs (screening) by thermal desorption and GC -MS / [Method document (opens in a new tab)](https://www.cdc.gov/niosh/docs/2003-154/pdfs/2549.pdf) | Active (pump) | Anasorb GCB2/GCB1/Carbosieve S-111 thermal desorption tube | | [226-330](https://analyt-mtc.com/catalog/product/skc-thermal-desorption-sorbent-tubes/#part-226-330) | | **NIOSH 2555** / Ketones by GC-FID / [Method document (opens in a new tab)](http://www.cdc.gov/niosh/docs/2003-154/pdfs/2555.pdf) | Active (pump) | Anasorb CMS tube (150/75mg) | GC-FID | | | **OSHA 1004** / 2-Butanone & Hexone by GC-FID / [Method document (opens in a new tab)](https://www.osha.gov/sites/default/files/methods/osha-1004.pdf) | Active (pump) | Anasorb CMS tubes (150/75mg) | | | | **OSHA 1004** / 2-Butanone & Hexone by GC-FID / [Method document (opens in a new tab)](https://www.osha.gov/sites/default/files/methods/osha-1004.pdf) | Passive | Passive sampler | GC-FID | [575-002](https://analyt-mtc.com/catalog/product/skc-organic-vapour-passive-samplers/#part-575-002) | | **OSHA 1004** | | | GC-FID | | | **OSHA 1004** | | | GC-FID | | | **EPA TO-17** | Active (pump) | | TD, GC | [226-350](https://analyt-mtc.com/catalog/product/skc-anasorb-sorbent-tubes/#part-226-350) / [226-347](https://analyt-mtc.com/catalog/product/skc-anasorb-sorbent-tubes/#part-226-347) / [224-26-02](https://analyt-mtc.com/catalog/product/skc-gas-and-vapour-sampling-accessories/#part-224-26-02) / [224-26-CPC](https://analyt-mtc.com/catalog/product/skc-gas-and-vapour-sampling-accessories/#part-224-26-cpc) | | **EPA TO-17** / VOCs by thermal desorption and GC / [Method document (opens in a new tab)](https://www.epa.gov/sites/default/files/2019-11/documents/to-17r.pdf) | Active (pump) | Two Thermal Desorption tubes | | | | **EPA TO-17** / Toxic Organic Compounds by thermal desorption and GC / [Method document (opens in a new tab)](http://www.epa.gov/ttn/amtic/files/ambient/airtox/to-17r.pdf) | Passive | Passive sampler | | | | **Non-agency** / Methyl isobutyl ketone by Colorimetric analysis | Direct-reading | Gastec detector tube | | [810-153](https://analyt-mtc.com/catalog/product/gastec-colour-gas-detector-tubes/#part-gst-153) / [810-153L](https://analyt-mtc.com/catalog/product/gastec-colour-gas-detector-tubes/#part-gst-153l) | | **Non-agency** / VOCs by solvent extraction and GC / [Method document (opens in a new tab)](https://www.skcltd.com/images/pdfs/ULTRA_Selection_Guide_April_2017.pdf) | Passive | Anasorb CSC (500mg) passive sampler | | [690-105](https://analyt-mtc.com/catalog/product/skc-ultra-passive-samplers/#part-690-105) | | **Non-agency** / VOCs by thermal desorption and GC / [Method document (opens in a new tab)](https://www.skcltd.com/images/pdfs/ULTRA_Selection_Guide_April_2017.pdf) | Passive | Anasorb GBC1 (370mg) or Chromosorb 106 (285 mg) passive sampler | | [690-101](https://analyt-mtc.com/catalog/product/skc-ultra-passive-samplers/#part-690-101) / [690-103](https://analyt-mtc.com/catalog/product/skc-ultra-passive-samplers/#part-690-103) | | **Non-agency** / Methyl isobutyl ketone by Colorimetric analysis | Passive | Gastec Dosi-tube | | [810-151D](https://analyt-mtc.com/catalog/product/gastec-passive-dosi-tubes/#part-gst-151d) / [810-152D](https://analyt-mtc.com/catalog/product/gastec-passive-dosi-tubes/#part-gst-152d) | | **Other** | Passive | | GC-FID | [575-001](https://analyt-mtc.com/catalog/product/skc-organic-vapour-passive-samplers/#part-575-001) | | **Other** | Passive | | GC-FID | [575-002](https://analyt-mtc.com/catalog/product/skc-organic-vapour-passive-samplers/#part-575-002) | | **Other** | Passive | | TD, GC | [690-101](https://analyt-mtc.com/catalog/product/skc-ultra-passive-samplers/#part-690-101) / [690-103](https://analyt-mtc.com/catalog/product/skc-ultra-passive-samplers/#part-690-103) | | **Other** | Passive | | GC-FID | [690-105](https://analyt-mtc.com/catalog/product/skc-ultra-passive-samplers/#part-690-105) | | **Other** | Passive | | DR | [810-152D](https://analyt-mtc.com/catalog/product/gastec-passive-dosi-tubes/#part-gst-152d) / [810-151D](https://analyt-mtc.com/catalog/product/gastec-passive-dosi-tubes/#part-gst-151d) | | **Other Internal** | Passive | | TD, GC | [690-101](https://analyt-mtc.com/catalog/product/skc-ultra-passive-samplers/#part-690-101) / [690-103](https://analyt-mtc.com/catalog/product/skc-ultra-passive-samplers/#part-690-103) | | **Other Internal** | Passive | | GC-FID | [690-105](https://analyt-mtc.com/catalog/product/skc-ultra-passive-samplers/#part-690-105) | Methods and limits as published by their agencies and summarised by SKC; check the current method and the limit that applies to you before sampling. Source: [SKC Ltd (UK), Hazard Search, used with SKC's permission (opens in a new tab)](https://www.skcltd.com/hazard-search.html); [SKC Inc. (USA), Sampling Guides, used with SKC's permission (opens in a new tab)](https://international.skcinc.com/sampling-guides/)