---
title: "Maleic anhydride (108-31-6): exposure limits and sampling"
url: https://analyt-mtc.com/tools/hazard-search/maleic-anhydride-108-31-6/
lang: en
alternates:
  en: https://analyt-mtc.com/tools/hazard-search/maleic-anhydride-108-31-6/
  de: https://analyt-mtc.com/de/tools/gefahrstoffsuche/maleic-anhydride-108-31-6/
---

Hazard search

# Maleic anhydride

CAS number

108-31-6

Also known as

2,5-Furandione · Dihydro-2,5-dioxofuran

## UK workplace exposure limits

| Limit | Value | Applies to |
| --- | --- | --- |
| 8-hour TWA | 1 mg/m³ |  |
| 15-minute STEL | 3 mg/m³ |  |

### Notations

-   Sen: can cause sensitisation

## Sampling methods

| Method | Sampling | Medium | Analysis | Part numbers |
| --- | --- | --- | --- | --- |
| **MDHS 72** / VOCs by thermal desorption and GC / [Method document (opens in a new tab)](http://www.hse.gov.uk/pubns/mdhs/pdfs/mdhs72.pdf) | Active (pump) | Tenax thermal desorption tube (250mg) | TD, GC | [226-357](https://analyt-mtc.com/catalog/product/skc-tenax-sorbent-tubes/#part-226-357) |
| **MDHS 104** / VOCs by thermal desorption and GC / [Method document (opens in a new tab)](https://www.hse.gov.uk/pubns/mdhs/pdfs/mdhs104.pdf) | Active (pump) | Tenax TD tube (250mg) |  | [226-357](https://analyt-mtc.com/catalog/product/skc-tenax-sorbent-tubes/#part-226-357) |
| **NIOSH 3512** / Maleic anhydride by HPLC/UV / [Method document (opens in a new tab)](http://www.cdc.gov/niosh/docs/2003-154/pdfs/3512.pdf) | Active (pump) | Fritted impinger | HPLC-UV | [225-36-2](https://analyt-mtc.com/catalog/product/skc-impingers/#part-225-36-2) / [225-22](https://analyt-mtc.com/catalog/product/biosampler/#part-225-22) |
| **OSHA 86** / Maleic anhydride by HPLC/UV / [Method document (opens in a new tab)](https://www.osha.gov/sites/default/files/methods/osha-86.pdf) | Active (pump) | Coated glass fibre filter in cassette | HPLC-UV | [225-9021](https://analyt-mtc.com/catalog/product/skc-coated-treated-filters/#part-225-9021) / [225-1](https://analyt-mtc.com/catalog/product/aluminium-respirable-dust-cyclone/#part-225-1) |
| **EPA TO-17** | Active (pump) |  | TD, GC | [226-350](https://analyt-mtc.com/catalog/product/skc-anasorb-sorbent-tubes/#part-226-350) / [226-347](https://analyt-mtc.com/catalog/product/skc-anasorb-sorbent-tubes/#part-226-347) / [224-26-02](https://analyt-mtc.com/catalog/product/skc-gas-and-vapour-sampling-accessories/#part-224-26-02) / [224-26-CPC](https://analyt-mtc.com/catalog/product/skc-gas-and-vapour-sampling-accessories/#part-224-26-cpc) |
| **EPA TO-17** / VOCs by thermal desorption and GC / [Method document (opens in a new tab)](https://www.epa.gov/sites/default/files/2019-11/documents/to-17r.pdf) | Active (pump) | Two Thermal Desorption tubes |  |  |
| **EPA TO-17** / Toxic Organic Compounds by thermal desorption and GC / [Method document (opens in a new tab)](http://www.epa.gov/ttn/amtic/files/ambient/airtox/to-17r.pdf) | Passive | Passive sampler |  |  |
| **Non-agency** / Maleic anhydride by HPLC/UV (as per OSHA 86) | Active (pump) | IOM & coated filter |  | [225-70A](https://analyt-mtc.com/catalog/product/haz-dust-7204-particulate-monitor/#part-225-70a) / [225-9028](https://analyt-mtc.com/catalog/product/skc-coated-treated-filters/#part-225-9028) |
| **Non-agency** / Maleic anhydride by Colorimetric analysis | Direct-reading | Gastec detector tube |  | [810-81](https://analyt-mtc.com/catalog/product/gastec-colour-gas-detector-tubes/#part-gst-81) |

Methods and limits as published by their agencies and summarised by SKC; check the current method and the limit that applies to you before sampling.

Source: [SKC Ltd (UK), Hazard Search, used with SKC's permission (opens in a new tab)](https://www.skcltd.com/hazard-search.html); [SKC Inc. (USA), Sampling Guides, used with SKC's permission (opens in a new tab)](https://international.skcinc.com/sampling-guides/)