---
title: "Dimethyl sulphate (77-78-1): exposure limits and sampling"
url: https://analyt-mtc.com/tools/hazard-search/dimethyl-sulphate-77-78-1/
lang: en
alternates:
  en: https://analyt-mtc.com/tools/hazard-search/dimethyl-sulphate-77-78-1/
  de: https://analyt-mtc.com/de/tools/gefahrstoffsuche/dimethyl-sulphate-77-78-1/
---

Hazard search

# Dimethyl sulphate

CAS number

77-78-1

Also known as

Dimethyl monosulphate · DMS · Sulphuric acid dimethyl ester

## UK workplace exposure limits

| Limit | Value | Applies to |
| --- | --- | --- |
| 8-hour TWA | 0.05 ppm |  |
| 8-hour TWA | 0.26 mg/m³ |  |

### Notations

-   Carc: carcinogen
-   Sk: can be absorbed through the skin

## Sampling methods

| Method | Sampling | Medium | Analysis | Part numbers |
| --- | --- | --- | --- | --- |
| **MDHS 89** | Active (pump) |  | GC-MS | [226-357](https://analyt-mtc.com/catalog/product/skc-tenax-sorbent-tubes/#part-226-357) |
| **MDHS 96** / VOCs by solvent desorption and GC / [Method document (opens in a new tab)](http://www.hse.gov.uk/pubns/mdhs/pdfs/mdhs96.pdf) | Active (pump) | Porapak-Q tube (100/50mg) | GC-ECN | [226-114](https://analyt-mtc.com/catalog/product/skc-porapak-sorbent-tubes/#part-226-114) |
| **MDHS 104** / VOCs by thermal desorption and GC / [Method document (opens in a new tab)](https://www.hse.gov.uk/pubns/mdhs/pdfs/mdhs104.pdf) | Active (pump) | Tenax TD tube (250mg) |  | [226-357](https://analyt-mtc.com/catalog/product/skc-tenax-sorbent-tubes/#part-226-357) |
| **NIOSH 2524** / Dimethyl sulphate by GC-ECD / [Method document (opens in a new tab)](http://www.cdc.gov/niosh/docs/2003-154/pdfs/2524.pdf) | Active (pump) | Porapak Q tube (100/50mg) | GC-ECN | [226-114](https://analyt-mtc.com/catalog/product/skc-porapak-sorbent-tubes/#part-226-114) |
| **OSHA PV2147** / Dimethyl sulphate by GC-FPD / [Method document (opens in a new tab)](https://www.osha.gov/sites/default/files/methods/osha-pv2147.pdf) | Active (pump) | Porapak-Q tube (150/75mg) | GC-FPD | [226-115](https://analyt-mtc.com/catalog/product/skc-porapak-sorbent-tubes/#part-226-115) |
| **Non-agency** / VOCs by solvent desorption and GC-FID / [Method document (opens in a new tab)](https://www.skcltd.com/images/pdfs/VOC_Chek_575_Series-Selection_Guide.pdf) | Passive | Passive sampler |  | [575-001](https://analyt-mtc.com/catalog/product/skc-organic-vapour-passive-samplers/#part-575-001) / [575-002](https://analyt-mtc.com/catalog/product/skc-organic-vapour-passive-samplers/#part-575-002) |

Methods and limits as published by their agencies and summarised by SKC; check the current method and the limit that applies to you before sampling.

Source: [SKC Ltd (UK), Hazard Search, used with SKC's permission (opens in a new tab)](https://www.skcltd.com/hazard-search.html); [SKC Inc. (USA), Sampling Guides, used with SKC's permission (opens in a new tab)](https://international.skcinc.com/sampling-guides/)